REGENERATIVE MEDICINE Concise Review: Therapeutic Potential of Mesenchymal Stem Cells fortheTreatment of Acute Liver Failure and Cirrhosis VLADISLAV VOLAREVIC, JASMIN NURKOVIC, NEBOJSA ARSENIJEVIC, MIODRAG S Key Words. Mesenchymal stem cell • Therapy • Acute liver failure • Cirrhosis

doi:10.1002/jgh3.12027 CASE REPORT Mesenchymalstemcell therapyforadvancedlivercirrhosis: A case report Ruveena Rajaram,* Baskar Subramani,† Basri J J Abdullah* and Sanjiv Mahadeva* *Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya Medical Centre, Kuala Lumpur and †Nichi-Asia Life Science Sdn Bhd, Petaling Jaya, Malaysia

Yao et al. Stem Cell Research & Therapy (2022) 13:308 https://doi.org/10.1186/s13287-022-03001-z REVIEW | OpenAccess Mesenchymal stromal cells: promising treatment for liver cirrhosis Lichao Yao†, Xue Hu†, Kai Dai, Mengqin Yuan, Pingji Liu, Qiuling Zhang and Yingan Jiang*

doi:10.1002/jgh3.12466 CASE REPORT Can bone marrow-derived mesenchymal stem cells change liver volume?: A case report Kwangmin Kim,*,†,‡ In Sik Shin,*,‡ Hui-Jae Bang,*,‡ Sanghyun An,*,‡ Gaesung Ha,*,‡ Hyun Soo Kim§,¶ and Keum Seok Bae*,† *Department of Surgery, Yonsei University Wonju College of Medicine, †Trauma Center, ‡Wonju Severance Surgical Research Group, Wonju Severance Christian Hospital, Wonju, §Pharmicell Co., Ltd., Sungnam and ¶Kim’s Stem Cell Clinic, Seoul, South Korea

Jiaetal.StemCellResearch&Therapy (2020) 11:277 https://doi.org/10.1186/s13287-020-01787-4 RESEARCH | OPEN ACCESS Enhanced therapeutic effects of umbilical cord mesenchymal stem cells after prolonged treatment for HBV-related liver failure and liver cirrhosis YifanJia1†,XinShu1†,XiaoanYang1,HaixiaSun1,HuijuanCao1,HongCao1*,KaZhang1* ,QihuanXu1,Gang Li1 and Yang Yang2

Am J Physiol Gastrointest Liver Physiol 309: G791–G800, 2015. First published August 27, 2015; doi:10.1152/ajpgi.00036.2015. Review CALL FOR PAPERS | Intestinal Stem Cells in GI Physiology and Disease Mesenchymal stromal cell therapy in liver disease: opportunities and lessons to be learnt? Andrew Owen1 and Philip N. Newsome National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver Research, Birmingham, United Kingdom; and Liver Unit, University Hospital Birmingham National Health Service Foundation Trust, Birmingham, United Kingdom Submitted 9 February 2015; accepted in final form 24 August 2015

Submit a Manuscript: http://www.wjgnet.com/esps/ Help Desk: http://www.wjgnet.com/esps/helpdesk.aspx DOI: 10.3748/wjg.v20.i38.14051 ---------------------------------------- WorldJGastroenterol 2014October 14;20(38): 14051-14057 ISSN 1007-9327 (print) ISSN 2219-2840 (online) © 2014 Baishideng Publishing Group Inc. All rights reserved. META-ANALYSIS Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis Xing-Nan Pan, Lian-Qiu Zheng, Xiao-Huan Lai

INTERNATIONAL JOURNAL OF REGENERATIVE MEDICINE | ISSN 2613-5914 Available online at www.sciencerepository.org Science Repository Research Article A Phase II Dose Escalation Study of Intraarterial (Hepatic) Adult Human Bone Marrow Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells (Stempeucel®) in Patients with Alcoholic Liver Cirrhosis Pawan Kumar Gupta1*, Anoop Chullikana1, Raviraja NS2, Udaykumar K1, Shivashankar P1, Pachaiyappan Viswanathan1, Mithun Chandrashekar2, Charan Thej1, Prasanth KV1, Jijy Abraham1 and Anish Sen Majumdar1 Stempeutics Research Pvt. Ltd., Manipal Hospitals Whitefield Pvt. Ltd., Bengaluru, Karnataka, India Stempeutics Research Pvt. Ltd., Shirdi Sai Baba Cancer Hospital, Manipal, Karnataka, India

HEPATOLOGY, VOL. 66, NO. 1, 2017 Allogeneic Bone Marrow–Derived Mesenchymal Stromal Cells for Hepatitis B Virus–Related Acute-on-Chronic Liver Failure: A Randomized Controlled Trial Bing-liang Lin, Jun-feng Chen, Wei-hong Qiu, Ke-wei Wang, Dong-ying Xie, Xiao-yong Chen, Qiu-li Liu, Liang Peng, Jian-guo Li, Yong-yu Mei, Wei-zhen Weng, Yan-wen Peng, Hui-juan Cao, Jun-qiang Xie, Shi-bin Xie, Andy Peng Xiang, and Zhi-liang Gao

Liu et al. Stem Cell Research & Therapy (2022) 13:204 https://doi.org/10.1186/s13287-022-02882-4 REVIEW | Open Access The assessment of mesenchymal stem cells therapy in acute on chronic liver failure and chronic liver disease: a systematic review and meta-analysis of randomized controlled clinical trials Yuwei Liu1,2 | Yutong Dong1,2 | Xiaojing Wu1,2 | Xiaotong Xu1,2 | Junqi Niu1,2*